A case of neurofibromatosis 1 presenting with optic pathway glioma with an early onset and an aggressive course

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منابع مشابه

High-Dose Intravenous Vitamin C Treatment of a Child with Neurofibromatosis Type 1 and Optic Pathway Glioma: A Case Report

BACKGROUND In neurofibromatosis type 1 (NF1) disease, the loss of the tumor suppressor function of the neurofibromin gene leads to proliferation of neural tumors. In children, the most frequently identified tumor is the optic pathway glioma. CASE REPORT We describe the case of a 5-year-old child who was diagnosed with NF1 and optic pathway tumor onset at the age of 14 months. Because of the tum...

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Non-optic glioma in adults and children with neurofibromatosis 1

BACKGROUND Non-optic gliomas occur in 5% of children with NF1, but little is known about these tumours in adults. We aimed to investigate progression, spontaneous regression and the natural history of non-optic gliomas in adults and compare these findings to the results found in children. RESULTS One thousand seven hundred twenty-two brain MRI scans of 562 unselected individuals with NF1 were...

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Detection of tumor progression in optic pathway glioma with and without neurofibromatosis type 1.

BACKGROUND We wanted to determine the sensitivity and specificity of serial changes in visual acuity and visual evoked potentials (VEPs) to detect radiological progression of tumor volume in children with optic pathway gliomas. METHODS From a retrospective review of a cohort of 69 patients, 54 patients met inclusion criteria (31 with primary chemotherapy, 4 with primary radiotherapy, and 19 w...

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a comparison of teachers and supervisors, with respect to teacher efficacy and reflection

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ژورنال

عنوان ژورنال: Indian Journal of Ophthalmology

سال: 2008

ISSN: 0301-4738

DOI: 10.4103/0301-4738.39128